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olympus bx51 wi dsu  (Olympus)


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    Olympus olympus bx51 wi dsu
    5XFAD mice lacking KChIP3 (5XFAD/KChIP3 −/− ) increases microglia accumulation around βA plaques. Representative micrographs of βA plaques (Thioflavina-S, green) and microglia (Iba1, red) on ( a ) prefrontal cortex (CTX) and ( b ) dentate gyrus (DG) from WT, KChIP3 −/− , 5XFAD and 5XFAD/KChIP3 −/− . Magnification shows microglia accumulation around βA plaque on orthogonal views. Signal was captured using an Olympus FluoView 1000 inverted confocal multiphoton microscope. Scale bars: 100 μm <t>20X;</t> and 50 μm in magnification 150X (60X objective lens with 2.5 digital zoom). Data were analyzed by unpaired T-test (*** p < 0.0001). n = 100 plaques from 2 male mice of 11 months old
    Olympus Bx51 Wi Dsu, supplied by Olympus, used in various techniques. Bioz Stars score: 99/100, based on 2950 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    1) Product Images from "KChIP3 fosters neuroinflammation and synaptic dysfunction in the 5XFAD mouse model of Alzheimer’s disease"

    Article Title: KChIP3 fosters neuroinflammation and synaptic dysfunction in the 5XFAD mouse model of Alzheimer’s disease

    Journal: Journal of Neuroinflammation

    doi: 10.1186/s12974-025-03426-2

    5XFAD mice lacking KChIP3 (5XFAD/KChIP3 −/− ) increases microglia accumulation around βA plaques. Representative micrographs of βA plaques (Thioflavina-S, green) and microglia (Iba1, red) on ( a ) prefrontal cortex (CTX) and ( b ) dentate gyrus (DG) from WT, KChIP3 −/− , 5XFAD and 5XFAD/KChIP3 −/− . Magnification shows microglia accumulation around βA plaque on orthogonal views. Signal was captured using an Olympus FluoView 1000 inverted confocal multiphoton microscope. Scale bars: 100 μm 20X; and 50 μm in magnification 150X (60X objective lens with 2.5 digital zoom). Data were analyzed by unpaired T-test (*** p < 0.0001). n = 100 plaques from 2 male mice of 11 months old
    Figure Legend Snippet: 5XFAD mice lacking KChIP3 (5XFAD/KChIP3 −/− ) increases microglia accumulation around βA plaques. Representative micrographs of βA plaques (Thioflavina-S, green) and microglia (Iba1, red) on ( a ) prefrontal cortex (CTX) and ( b ) dentate gyrus (DG) from WT, KChIP3 −/− , 5XFAD and 5XFAD/KChIP3 −/− . Magnification shows microglia accumulation around βA plaque on orthogonal views. Signal was captured using an Olympus FluoView 1000 inverted confocal multiphoton microscope. Scale bars: 100 μm 20X; and 50 μm in magnification 150X (60X objective lens with 2.5 digital zoom). Data were analyzed by unpaired T-test (*** p < 0.0001). n = 100 plaques from 2 male mice of 11 months old

    Techniques Used: Microscopy



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    5XFAD mice lacking KChIP3 (5XFAD/KChIP3 −/− ) increases microglia accumulation around βA plaques. Representative micrographs of βA plaques (Thioflavina-S, green) and microglia (Iba1, red) on ( a ) prefrontal cortex (CTX) and ( b ) dentate gyrus (DG) from WT, KChIP3 −/− , 5XFAD and 5XFAD/KChIP3 −/− . Magnification shows microglia accumulation around βA plaque on orthogonal views. Signal was captured using an Olympus FluoView 1000 inverted confocal multiphoton microscope. Scale bars: 100 μm 20X; and 50 μm in magnification 150X (60X objective lens with 2.5 digital zoom). Data were analyzed by unpaired T-test (*** p < 0.0001). n = 100 plaques from 2 male mice of 11 months old

    Journal: Journal of Neuroinflammation

    Article Title: KChIP3 fosters neuroinflammation and synaptic dysfunction in the 5XFAD mouse model of Alzheimer’s disease

    doi: 10.1186/s12974-025-03426-2

    Figure Lengend Snippet: 5XFAD mice lacking KChIP3 (5XFAD/KChIP3 −/− ) increases microglia accumulation around βA plaques. Representative micrographs of βA plaques (Thioflavina-S, green) and microglia (Iba1, red) on ( a ) prefrontal cortex (CTX) and ( b ) dentate gyrus (DG) from WT, KChIP3 −/− , 5XFAD and 5XFAD/KChIP3 −/− . Magnification shows microglia accumulation around βA plaque on orthogonal views. Signal was captured using an Olympus FluoView 1000 inverted confocal multiphoton microscope. Scale bars: 100 μm 20X; and 50 μm in magnification 150X (60X objective lens with 2.5 digital zoom). Data were analyzed by unpaired T-test (*** p < 0.0001). n = 100 plaques from 2 male mice of 11 months old

    Article Snippet: 40 well-stained pyramidal neurons from the CA1 region of the dorsal hippocampus (bregma –2.03 to –2.27 mm), [ ] of each experimental group (ten neurons per mouse) were identified and captured in an Olympus BX51-WI-DSU (Disk Scanning Unit) microscope (Olympus, Tokyo, Japan; Objective Microscope: 20x) coupled to the Stereoinvestigator 9 R software (MBF Bioscience, Williston, VT, US).

    Techniques: Microscopy